AN UNBIASED VIEW OF TILIDIN PROSPECT

Just after oral administration, tilidine is quickly absorbed. It's issue to your pronounced very first-go effect. The conversion of tilidine to the more strong active metabolite nortilidine happens with the involvement of CYP3A4 and CYP2C19. Inhibition of those enzymes could thus alter the efficacy and tolerability profile of tilidine.Tinidine synt